Rea anchors Chicago’s rotation in this pivotal series with a 4.09 ERA and a recent seven‐inning, two‐run effort that underscored his ability to mix looks and location. His ability to navigate a Pirates offense will be a barometer for Chicago’s chances to swing this set in their favor.

Rea headlines the Cubs’ matinee, carrying a strong track record entering this start. His presence adds a test for Pittsburgh’s lineup, and his performance will heavily influence the early tempo of the game and Chicago’s ability to leverage early runs.

Rea faces Reynolds in a day game at Wrigley, a setup that compounds Reynolds’ power upside against right-handed pitching. Rea has had varied results this season with lefty-heavy power exposure and a higher homer rate to left-handed bats; this spot is a potential drag on Reynolds’ prop but a consideration for the Cubs’ defense and bullpen.

Rea sits in Cubs’ rotation depth as Assad lands on the 40-man; Rea’s role is tied to roster moves and Taillon’s health. His presence provides the Cubs an option for long-relief or spot-starter duty if needed, helping stabilize a staff still finding its footing with Amaya and Taillon back.

Colin Rea is noted as the Cubs' starter with HR-susceptible tendencies, presenting Burleson as the value play in this matchup. Rea’s HR-per-nine context and his 75-inning threshold anchor a narrative where Burleson’s power upside becomes particularly actionable against a Cubs pitcher giving up dingers.